0.2% IVERMECTIN DRENCH
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Pharmacological kanthu
Ivermectinmakamaka ali wabwino anthelmintic zotsatira nematodes ndi pamwamba arthropods mu vivo.Kachitidwe kake ka anthelmintic ndikulimbikitsa kutulutsidwa kwa γ-aminobutyric acid (GABA) kuchokera ku presynaptic neurons, potero kutsegula njira za GABA-mediated chloride.Ivermectin imakhalanso yosankha komanso yogwirizana kwambiri ndi njira za glutamate-mediated chloride zomwe zili pafupi ndi malo a GABA-mediated mu invertebrate nerve ndi maselo a minofu, potero amalepheretsa kufalikira kwa chizindikiro pakati pa minofu ya neuromuscular ndi kupumula ndi kupumitsa tizilombo toyambitsa matenda, zomwe zimapangitsa kuti tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda kapena kuthamangitsidwa. thupi.The inhibitory interneurons ndi excitatory motoneurons ya C. elegans ndi malo awo ochitirapo kanthu, pamene malo a arthropods ndi neuromuscular junction.Zimagwiranso ntchito polimbana ndi tizilombo toyambitsa matenda, monga mphutsi, nthata, ndi nsabwe.wamkulu Coronaria dentata ndi mwana majeremusi mu nkhumba, ndi zothandiza kwambiri kwa Trichinella spiralis mu intestine (osagwira mu mnofu Trichinella spiralis), komanso ali ndi kulamulira bwino pa nsabwe magazi nkhumba ndi Sarcoptes mphere.Sichigwira ntchito motsutsana ndi trematodes ndi tapeworms.
Pharmacokinetics
Ma pharmacokinetics aivermectinzimasiyana mosiyanasiyana kutengera mtundu wa nyama, mawonekedwe a mlingo, ndi njira yoyendetsera.The bioavailability wa subcutaneous jakisoni ndi apamwamba kuposa makonzedwe a pakamwa, koma pakamwa makonzedwe amatengedwa mofulumira kuposa subcutaneous jekeseni.Pambuyo pa kuyamwa, imatha kugawidwa bwino kumagulu ambiri, koma sikophweka kulowa mu cerebrospinal fluid.Kuchuluka kwa kugawa kwa nkhosa ndi nkhumba ndi 4.6 ndi 4 L / kg, motero.Ili ndi theka la moyo wautali mu nyama zambiri, 2 mpaka 7 ndi masiku 0.5 mu nkhosa ndi nkhumba, motero.Izi zimapukusidwa m'chiwindi, makamaka hydroxylated mu nkhosa, ndipo makamaka methylated mu nkhumba.Imatulutsidwa makamaka mu ndowe ndipo ochepera 5% amachotsedwa mosasinthika kapena ngati metabolites mumkodzo.M'madamu oyamwitsa, 5% ya mlingo amachotsedwa mkaka.
Kugwiritsa Ntchito Mankhwala
Kugwiritsa ntchito munthawi yomweyo ndi diethylcarbamazine kumatha kubweretsa zovuta kapena kufa kwa encephalopathy.
Zochita ndi kugwiritsa ntchito
Macrolide antiparasite mankhwala.Amagwiritsidwa ntchito polimbana ndi nematode, acariasis ndi matenda a tizilombo toyambitsa matenda a nkhosa ndi nkhumba.
Mlingo ndi makonzedwe
Pakamwa: mlingo umodzi, 0,1 ml ya nkhosa ndi 0,15 ml ya nkhumba pa 1 kg ya kulemera kwa thupi.
Zoyipa
Palibe zoyipa zomwe zawonedwa zikagwiritsidwa ntchito molingana ndi kagwiritsidwe kake komanso mlingo wake.
Kusamalitsa
(1) Ndi contraindicated pa mkaka wa m`mawere.
(2) Ayenera kugwiritsidwa ntchito mosamala akamakula m’masiku 45 oyambirira a mimba.
(3) Ivermectin shrimp, nsomba ndi zamoyo zam'madzi ndi poizoni kwambiri, ndipo kulongedza ndi mbiya za mankhwala otsalira sayenera kuipitsa magwero a madzi.
Nthawi yochotsa: masiku 35 a nkhosa ndi masiku 28 a nkhumba.
Nthawi yochotsa
Masiku 35 kwa nkhosa ndi masiku 28 kwa nkhumba.
Hebei Veyong pharmaceutical Co., Ltd, unakhazikitsidwa mu 2002, ili mu Shijiazhuang City, Hebei Province, China, pafupi ndi Capital Beijing.Ndi kampani yayikulu yovomerezeka ya GMP yotsimikizira za Chowona Zanyama, yokhala ndi R&D, kupanga ndi kugulitsa ma API a Chowona Zanyama, kukonzekera, zakudya zosakaniza ndi zowonjezera zowonjezera.Monga Provincial Technical Center, Veyong yakhazikitsa njira yatsopano ya R&D yamankhwala atsopano azowona zanyama, ndipo ndi kampani yodziwika bwino yaukadaulo yozikidwa pazanyama, pali akatswiri 65 aukadaulo.Veyong ili ndi zoyambira ziwiri zopangira: Shijiazhuang ndi Ordos, pomwe maziko a Shijiazhuang amatenga malo a 78,706 m2, okhala ndi zinthu 13 za API kuphatikiza Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, ndi 11, mizere yopangira jekeseni, njira yopangira jekeseni. , premix, bolus, mankhwala ndi mankhwala ophera tizilombo, ects.Veyong imapereka ma API, zokonzekera zolembera zopitilira 100, ndi ntchito za OEM & ODM.
Veyong amawona kufunikira kwakukulu ku kasamalidwe ka EHS(Environment, Health & Safety) system, ndipo adalandira ziphaso za ISO14001 ndi OHSAS18001.Veyong adalembedwa m'mabizinesi omwe akutuluka m'chigawo cha Hebei ndipo amatha kuonetsetsa kuti zinthu zikuyenda bwino.
Veyong adakhazikitsa dongosolo lathunthu la kasamalidwe kaubwino, adapeza satifiketi ya ISO9001, satifiketi ya China GMP, satifiketi ya APVMA GMP ya Australia, satifiketi ya GMP ya Ethiopia, satifiketi ya Ivermectin CEP, ndipo idapita ku US FDA.Veyong ali ndi gulu la akatswiri olembetsa, malonda ndi ntchito zaukadaulo, kampani yathu idadalitsidwa ndi chithandizo kuchokera kwamakasitomala ambiri ndi mtundu wabwino kwambiri wazinthu, zogulitsa zapamwamba kwambiri komanso ntchito zotsatsa pambuyo pa malonda, kasamalidwe kakulu ndi sayansi.Veyong wapanga mgwirizano wautali ndi mabizinesi ambiri odziwika padziko lonse lapansi ogulitsa nyama ndi zinthu zomwe zimatumizidwa ku Europe, South America, Middle East, Africa, Asia, etc. mayiko ndi zigawo zopitilira 60.
