Tiamulin Hydrogen Fumarate

Kufotokozera Mwachidule:

Nambala ya CAS:55297-96-6

Molecular formula:Chithunzi cha C32H51NO8S

Tsatanetsatane wa Zamalonda

Zogulitsa Tags

Tiamulin hydrogen fumarate

Tiamulin hydrogen fumarate ndi chochokera ku pleuromutilin, angagwiritsidwe ntchito pa Chowona Zanyama makamaka nkhumba ndi nkhuku.Ndi diterpene antimicrobial ndi pleuromutilin mankhwala kapangidwe ofanana ndi valnemulin.

Tiamulin hydrogen fumarate ndi yoyera kapena pafupifupi ufa wa crystalline woyera, wopanda fungo komanso wosakoma.Imasungunuka mosavuta mu methanol kapena ethanol, imasungunuka m'madzi, imasungunuka pang'ono mu acetone, komanso pafupifupi osasungunuka mu hexane.

Kachitidwe kachitidwe ndi mawonekedwe

Mankhwalawa ndi bacteriostatic antibiotic, komanso amakhala ndi bactericidal pa mabakiteriya okhudzidwa kwambiri.Antibacterial limagwirira ntchito ndikuletsa kaphatikizidwe ka mapuloteni a bakiteriya pomanga gawo la 50s la bakiteriya ribosome.

Tiamulin hydrogen fumarate ili ndi antibacterial yabwino yolimbana ndi mitundu yosiyanasiyana ya Gram-positive cocci, kuphatikiza staphylococci ndi streptococci (kupatula gulu D streptococci) ndi mitundu yosiyanasiyana ya mycoplasmas ndi spirochetes.Komabe, antibacterial zochita motsutsana ndi mabakiteriya ena oyipa ndi ofooka kwambiri, kupatula mitundu ya Haemophilus ndi mitundu ina ya E. coli ndi Klebsiella.

Tiamulin hydrogen fumarate ndiyosavuta kuyamwa pambuyo poyendetsa pakamwa mu nkhumba.Pafupifupi 85% ya mlingo umodzi umatengedwa, ndipo nsonga zake zazikulu zimachitika pambuyo pa maola awiri kapena anayi.Imagawidwa kwambiri m'thupi, ndipo imakhala yochuluka kwambiri m'mapapu.Tiamulin hydrogen fumarate imapangidwa m'thupi kukhala ma metabolites 20, ena amakhala ndi bata la antibacterial.Pafupifupi 30% ya metabolites imatulutsidwa mumkodzo ndipo yotsalayo imatulutsidwa mu ndowe.

Kugwiritsa ntchito

Tiamulin hydrogen fumarate amagwiritsidwa ntchito pochiza chibayo cha nkhumba chifukwa cha Actinobacillus pleuropneumoniae ndi kamwazi yamagazi a nkhumba chifukwa cha Treponema hyodysenteriae.Monga chakudya chamankhwala chowonjezera cha nkhumba chimalimbikitsa kunenepa.Ndiwothandizanso polimbana ndi matenda opumira ankhuku, mycoplasma hyopneumonia, ndi staphylococcal synovitis mu nkhuku.