Ivermectin

Kufotokozera Mwachidule:

Nambala ya CAS: 70288-86-7

Mapangidwe a maselo: C48H74O14

Mankhwala odana ndi tiziromboti mankhwala

Zikalata: EU COS, US FDA, GMP, ISO9001

Zofotokozera: EP, BP, USP

Zomwe zili: ≥96%

Ubwino: Zonyansa zochepa

Chitsanzo: zilipo

Kuyika: 1kg / thumba la aluminiyamu.

Titumizireni imelo

Tsatanetsatane wa Zamalonda

Zogulitsa Tags

Ivermectin

Ivermectinndi ufa wonyezimira woyera, wopanda fungo.Amasungunuka momasuka mu methanol, ethanol, acetone, ethyl acetate, pafupifupi osasungunuka m'madzi, komanso hygroscopic pang'ono.Ivermectin ndi semisynthetic macrolide Mipikisano gawo mankhwala, amene makamaka lili ivermectin B1 (Bla + B1b) zili osachepera 95%, amene Bla zili zosachepera 85%.

Mfundo ya Mankhwala

Ivermectin ali kusankha chopinga tingati, ndi kumanga kwa mkulu kuyanjana kwa kolorayidi ngalande ndi glutamate monga valavu mu mitsempha maselo ndi minofu maselo a spinless nyama, kumabweretsa kuwonjezeka kwa permeability wa nembanemba selo kuti chloride ayoni, zimayambitsa hyperpolarization wa mitsempha maselo. kapena maselo a minofu, ndipo amachititsa ziwalo kapena kufa kwa tizilombo toyambitsa matenda.Imalumikizananso ndi njira za chloride za ma valve ena a ligand, monga neurotransmitter g-aminobutyric acid (GABA).Kusankhidwa kwa mankhwalawa ndi chifukwa chakuti zinyama zina zilibe njira za glutamate-chloride mu vivo, ndipo avermectin imakhala ndi chiyanjano chochepa cha mammalian ligand-chloride.Mankhwalawa sangalowe m'kati mwa ubongo wa munthu.Onchocerciasis ndi strongyloidiasis ndi nyongolotsi, ascaris, Trichuris trichiura, ndi matenda a Enterobius vermicularis.

Kugwiritsa

Ivermectin ndi mankhwala omwe amagwiritsidwa ntchito pochiza mitundu yambiri ya tizilombo toyambitsa matenda.Ivermectin amagwiritsidwa ntchito pochiza matenda a nyama omwe amayamba chifukwa cha mphutsi ndi ectoparasites.

Ivermectin nthawi zonse ntchito kulamulira parasitic nyongolotsi mu m`mimba thirakiti nyama ruminant.Tizilombo toyambitsa matenda timeneti timaloŵa m’chinyama chikamadya msipu, timadutsa m’matumbo, n’kukafika m’matumbo n’kukhwima, ndipo pambuyo pake timapanga mazira amene amachoka m’zitosi za nyamayo n’kukalowa msipu watsopano.Ivermectin imathandiza kupha ena, koma osati onse, a tizilombo toyambitsa matenda.

Mu mankhwala a Chowona Zanyama, amagwiritsidwa ntchito kuteteza ndi kuchiza matenda a mtima ndi acariasis, pakati pa zizindikiro zina.Itha kutengedwa pakamwa kapena kugwiritsidwa ntchito pakhungu chifukwa cha matenda akunja.Ivermectin chimagwiritsidwa ntchito m'mimba nematodes, mphutsi, ndi parasitic arthropods ng'ombe, nkhosa, akavalo, ndi nkhumba, matumbo nematodes mu agalu, nthata khutu, Sarcoptes scabiei, mtima filariae, ndi microfilariae, ndi m'mimba nematodes m'mimba ndi ematodes.