Ivermectin
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Kanema
Ivermectin
Ivermectinndi ufa wonyezimira woyera, wopanda fungo.Amasungunuka momasuka mu methanol, ethanol, acetone, ethyl acetate, pafupifupi osasungunuka m'madzi, komanso hygroscopic pang'ono.Ivermectin ndi semisynthetic macrolide Mipikisano gawo mankhwala, amene makamaka lili ivermectin B1 (Bla + B1b) zili osachepera 95%, amene Bla zili zosachepera 85%.
Mfundo ya Mankhwala
Ivermectin ali kusankha chopinga tingati, ndi kumanga kwa mkulu kuyanjana kwa kolorayidi ngalande ndi glutamate monga valavu mu mitsempha maselo ndi minofu maselo a spinless nyama, zomwe zimabweretsa kuwonjezeka kwa permeability wa nembanemba selo kuti chloride ayoni, zimayambitsa hyperpolarization wa mitsempha maselo. kapena maselo a minofu, ndipo amachititsa ziwalo kapena kufa kwa tizilombo toyambitsa matenda.Imalumikizananso ndi njira za chloride za ma valve ena a ligand, monga neurotransmitter g-aminobutyric acid (GABA).Kusankhidwa kwa mankhwalawa ndi chifukwa chakuti zinyama zina zilibe njira za glutamate-chloride mu vivo, ndipo avermectin imakhala ndi chiyanjano chochepa cha mammalian ligand-chloride.Chida ichi sichingalowe mu chotchinga chamagazi chamunthu.Onchocerciasis ndi strongyloidiasis ndi nyongolotsi, ascaris, Trichuris trichiura, ndi matenda a Enterobius vermicularis.
Kugwiritsa
Ivermectin ndi mankhwala omwe amagwiritsidwa ntchito pochiza mitundu yambiri ya tizilombo toyambitsa matenda.Ivermectin imagwiritsidwa ntchito pochiza matenda a nyama omwe amayamba chifukwa cha mphutsi ndi ectoparasites.
Ivermectin nthawi zonse ntchito kulamulira parasitic nyongolotsi mu m`mimba thirakiti nyama ruminant.Tizilombo toyambitsa matenda timeneti timaloŵa m’chilombocho pamene ikudya msipu, timadutsa m’matumbo, n’kukhazikika ndi kukhwima m’matumbo, ndipo pambuyo pake timapanga mazira amene amachoka m’zitosi za nyamayo n’kugwera msipu watsopano.Ivermectin imathandiza kupha ena, koma osati onse, a tizilombo toyambitsa matenda.
Mu mankhwala Chowona Zanyama, amagwiritsidwa ntchito kupewa ndi kuchiza heartworm ndi acariasis, pakati pa zizindikiro zina.Itha kutengedwa pakamwa kapena kugwiritsidwa ntchito pakhungu chifukwa cha matenda akunja.Ivermectin chimagwiritsidwa ntchito m'mimba nematodes, mphutsi, ndi parasitic arthropods ng'ombe, nkhosa, akavalo, ndi nkhumba, nematodes m'mimba mu agalu, nthata khutu, Sarcoptes scabiei, mtima filariae, ndi microfilariae, ndi m'mimba nematodes ndi m'mimba nematodes.
Kukonzekera
Ivermectin jakisoni1%,2%,3.4%,4%;
Ivermectin m'kamwa njira 0,08%, 0,8%, 0,2%;
Ivermectin premix;
Ivermectin bolus;
Ivermectin kutsanulira yankho 0.5%, 1% ;
Ivermectin gel osakaniza 0.4%
Hebei Veyong pharmaceutical Co., Ltd, unakhazikitsidwa mu 2002, ili mu Shijiazhuang City, Hebei Province, China, pafupi ndi Capital Beijing.Ndi kampani yayikulu yovomerezeka ya GMP yotsimikizira za Chowona Zanyama, yokhala ndi R&D, kupanga ndi kugulitsa ma API a Chowona Zanyama, kukonzekera, zakudya zosakaniza ndi zowonjezera zowonjezera.Monga Provincial Technical Center, Veyong yakhazikitsa njira yatsopano ya R&D yamankhwala atsopano azowona zanyama, ndipo ndi kampani yodziwika bwino yaukadaulo yozikidwa pazanyama, pali akatswiri 65 aukadaulo.Veyong ili ndi zoyambira ziwiri zopangira: Shijiazhuang ndi Ordos, pomwe maziko a Shijiazhuang amatenga malo a 78,706 m2, okhala ndi zinthu 13 za API kuphatikiza Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, ndi 11, mizere yopangira jekeseni, njira yopangira jekeseni. , premix, bolus, mankhwala ndi mankhwala ophera tizilombo, ects.Veyong imapereka ma API, zokonzekera zolembera zopitilira 100, ndi ntchito za OEM & ODM.
Veyong amawona kufunikira kwakukulu ku kasamalidwe ka EHS(Environment, Health & Safety) system, ndipo adalandira ziphaso za ISO14001 ndi OHSAS18001.Veyong adalembedwa m'mabizinesi omwe akutuluka m'chigawo cha Hebei ndipo amatha kuonetsetsa kuti zinthu zikuyenda bwino.
Veyong adakhazikitsa dongosolo lathunthu la kasamalidwe kaubwino, adapeza satifiketi ya ISO9001, satifiketi ya China GMP, satifiketi ya APVMA GMP ya Australia, satifiketi ya GMP ya Ethiopia, satifiketi ya Ivermectin CEP, ndipo idapita ku US FDA.Veyong ali ndi gulu la akatswiri olembetsa, malonda ndi ntchito zaukadaulo, kampani yathu idadalitsidwa ndi chithandizo kuchokera kwamakasitomala ambiri ndi mtundu wabwino kwambiri wazinthu, zogulitsa zapamwamba kwambiri komanso ntchito zotsatsa pambuyo pa malonda, kasamalidwe kakulu ndi sayansi.Veyong wapanga mgwirizano wautali ndi mabizinesi ambiri odziwika padziko lonse lapansi ogulitsa nyama ndi zinthu zomwe zimatumizidwa ku Europe, South America, Middle East, Africa, Asia, etc. mayiko ndi zigawo zopitilira 60.
