20% Florfenicol WSP
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Kanema
Pharmacodynamics
Florfenicol ndi anti-spectrum amide alcohol antibiotic ndi bacteriostatic agent, yomwe imagwira ntchito poletsa kaphatikizidwe ka mapuloteni a bakiteriya pomanga gawo la 50S la ribosome.Lili ndi mphamvu yolimbana ndi mabakiteriya osiyanasiyana a gram-positive ndi gram-negative.Pasteurella hemolytica, Pasteurella multocida, ndi Actinobacillus pleuropneumoniae amatengeka kwambiri ndi florfenicol.Mphamvu yolimbana ndi mabakiteriya a florfenicol polimbana ndi tizilombo tambiri ta mu m'galasi ndi yofanana kapena yamphamvu kuposa ya thiamphenicol, ndipo mabakiteriya ena omwe samva ma amide alcohols chifukwa cha acetylation, monga Escherichia coli ndi Klebsiella pneumoniae, amatha kukhala Omva florfenicol.
Amagwiritsidwa ntchito kwambiri pa matenda a bakiteriya a nkhumba, nkhuku ndi nsomba zomwe zimayambitsidwa ndi mabakiteriya okhudzidwa, monga matenda opuma a ng'ombe ndi nkhumba chifukwa cha Pasteurella hemolytica, Pasteurella multocida ndi Actinobacillus pleuropneumoniae.Matenda a typhoid ndi paratyphoid fever chifukwa cha Salmonella, kolera ya nkhuku, pullorum, Escherichia coli, etc.;mabakiteriya a nsomba omwe amayamba ndi Pasteurella, Vibrio, Staphylococcus aureus, Hydromonas, Enteritidis, etc. Sepsis, enteritis, matenda a khungu ofiira, etc.
Pharmacokinetics
Kuwongolera pakamwa kwa florfenicol kumayamwa mwachangu, ndipo ndende yochizira imatha kufikika m'magazi patatha pafupifupi ola limodzi, ndipo kuchuluka kwa magazi kumafikira maola 1 mpaka 3.The bioavailability ndi oposa 80%.Florfenicol imagawidwa kwambiri mu nyama ndipo imatha kudutsa chotchinga chamagazi ndi ubongo.Amachotsedwa makamaka mumkodzo, ndipo pang'ono amachotsedwa ndi ndowe.
Kuyanjana kwa mankhwala
(1) Macrolides ndi lincosamides ali ndi chandamale chofanana ndi mankhwalawa, onse amamangiriridwa ku gawo la 50S la bakiteriya ribosome, ndipo amatha kubweretsa kusagwirizana akagwiritsidwa ntchito limodzi.(2) Ikhoza kusokoneza ntchito ya bactericidal ya penicillin kapena aminoglycosides, koma sizinawonetsedwe mu zinyama.
Zochita ndi kugwiritsa ntchito
Amide mowa maantibayotiki.Kwa matenda a Pasteurella ndi Escherichia coli.
Kagwiritsidwe ndi Mlingo
Kutengera ndi mankhwalawa.Kuwongolera pakamwa: pa 1kg kulemera kwa thupi, 0.1 ~ 0.15g kwa nkhumba ndi nkhuku.2 pa tsiku kwa 3 mpaka 5 masiku.Nsomba 50 ~ 75mg.1 nthawi patsiku kwa masiku 3 mpaka 5.
Zoyipa
20% Florfenicol madzi osungunuka ufa ali ndi mphamvu ya immunosuppressive pamene amagwiritsidwa ntchito pa mlingo wapamwamba kuposa mlingo woyenera.
Chidwi
(1) Nkhuku zoikira mazira kuti anthu azidya siziyenera kugwiritsidwa ntchito panthawi yoikira dzira;(2) Kugwiritsa ntchito mosamala kwa oweta.Ili ndi embryotoxicity ndipo iyenera kugwiritsidwa ntchito mosamala pa ziweto zapakati komanso zoyamwitsa;(3) Ndi contraindicated pa katemera kapena nyama ndi kwambiri immunodeficiency;(4) Mu nyama zomwe zili ndi vuto laimpso, mlingo uyenera kuchepetsedwa moyenerera kapena nthawi ya dosing iyenera kukulitsidwa.
Nthawi yochotsa
masiku 20 nkhumba, masiku 5 nkhuku;375 digiri masiku nsomba.
Kusungirako
Pitirizani kusindikizidwa ndi malo ouma
Hebei Veyong pharmaceutical Co., Ltd, unakhazikitsidwa mu 2002, ili mu Shijiazhuang City, Hebei Province, China, pafupi ndi Capital Beijing.Ndi kampani yayikulu yovomerezeka ya GMP yotsimikizira za Chowona Zanyama, yokhala ndi R&D, kupanga ndi kugulitsa ma API a Chowona Zanyama, kukonzekera, zakudya zosakaniza ndi zowonjezera zowonjezera.Monga Provincial Technical Center, Veyong yakhazikitsa njira yatsopano ya R&D yamankhwala atsopano azowona zanyama, ndipo ndi kampani yodziwika bwino yaukadaulo yozikidwa pazanyama, pali akatswiri 65 aukadaulo.Veyong ili ndi zoyambira ziwiri zopangira: Shijiazhuang ndi Ordos, pomwe maziko a Shijiazhuang amatenga malo a 78,706 m2, okhala ndi zinthu 13 za API kuphatikiza Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, ndi 11, mizere yopangira jekeseni, njira yopangira jekeseni. , premix, bolus, mankhwala ndi mankhwala ophera tizilombo, ects.Veyong imapereka ma API, zokonzekera zolembera zopitilira 100, ndi ntchito za OEM & ODM.
Veyong amawona kufunikira kwakukulu ku kasamalidwe ka EHS(Environment, Health & Safety) system, ndipo adalandira ziphaso za ISO14001 ndi OHSAS18001.Veyong adalembedwa m'mabizinesi omwe akutuluka m'chigawo cha Hebei ndipo amatha kuonetsetsa kuti zinthu zikuyenda bwino.
Veyong adakhazikitsa dongosolo lathunthu la kasamalidwe kaubwino, adapeza satifiketi ya ISO9001, satifiketi ya China GMP, satifiketi ya APVMA GMP ya Australia, satifiketi ya GMP ya Ethiopia, satifiketi ya Ivermectin CEP, ndipo idapita ku US FDA.Veyong ali ndi gulu la akatswiri olembetsa, malonda ndi ntchito zaukadaulo, kampani yathu idadalitsidwa ndi chithandizo kuchokera kwamakasitomala ambiri ndi mtundu wabwino kwambiri wazinthu, zogulitsa zapamwamba kwambiri komanso ntchito zotsatsa pambuyo pa malonda, kasamalidwe kakulu ndi sayansi.Veyong wapanga mgwirizano wautali ndi mabizinesi ambiri odziwika padziko lonse lapansi ogulitsa nyama ndi zinthu zomwe zimatumizidwa ku Europe, South America, Middle East, Africa, Asia, etc. mayiko ndi zigawo zopitilira 60.
