20% Albendazole Granule
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Pharmacology
Albendazole ndi benzimidazole yochokera ku benzimidazole, yomwe imatha kupangidwa mwachangu m'thupi kukhala sulfoxide, sulfone mowa ndi 2-aminosulfone mowa.Iwo kusankha ndi irreversibly linalake ndipo tikulephera polymerization wa cytoplasmic microtubule dongosolo la tiziromboti m`mimba khoma maselo kwa matumbo nematodes, amene angalepheretse kutengera ndi mayamwidwe zosiyanasiyana zakudya ndi shuga, zikubweretsa kutopa amkati glycogen mu tizilombo, ndi inhibits. fumarate reductase Dongosolo limalepheretsa kupanga adenosine triphosphate ndikulepheretsa kukhala ndi moyo ndi kubereka kwa nyongolotsi.Mofanana ndi mebendazole, mankhwalawa angayambitsenso kuchepa kwa cytoplasmic microtubules ya maselo a matumbo a nyongolotsi, ndikumanga ku tubulin yake, kuchititsa kutsekeka kwa kayendedwe ka okhudza maselo ambiri, kuchititsa kudzikundikira kwa Golgi endocrine granules, cytoplasmic pang'onopang'ono kuvunda, ndi kuwonongeka kwathunthu kwa mayamwidwe. maselo.Zimayambitsa imfa ya mphutsi.20% Albendazole granuleimatha kupha mazira a nyongolotsi ndi mazira a chikwapu ndikuphanso mazira a nyongolotsi.Kuphatikiza pa kupha ndi kuthamangitsa ma nematode osiyanasiyana omwe ali ndi parasitic nyama, imakhalanso ndi zotsatira zoonekeratu zakupha ndi kuthamangitsa mphutsi za tapeworms ndi cysticercus.
Toxicology
Mayeso a Toxicological amasonyeza kuti mankhwalawa ali ndi kawopsedwe kakang'ono ndipo ndi otetezeka.Mkamwa LD50 ya mbewa ndi yayikulu kuposa 800mg/kg, ndipo mlingo wovomerezeka wa agalu ndi wopitilira 400mg/kg.Mankhwalawa alibe mphamvu pa ntchito yoberekera ya mbewa zamphongo, ndipo alibe teratogenic pa mbewa zachikazi.Kuyamwitsa kwa mwana wakhanda kumachitika pamene mlingo wokulirapo [30 mg/(㎏·tsi)] wapaka makoswe aakazi ndi akalulu aakazi.Ndi kupunduka kwa chigoba.
Kagwiritsidwe ndi Mlingo
Kuchokera pa albendazole.Kuwongolera pakamwa: kamodzi, 25 ~ 50mg / kg kulemera kwa thupi.Kapena tsatirani malangizo a dokotala.
Zoipa
(1) agalu akapatsidwa 50 mg / kg kawiri pa tsiku, pang'onopang'ono amayamba kukhala ndi anorexia
(2) Kugwiritsa ntchito albendazole kumayambiriro mimba akhoza limodzi ndi teratogenicity ndi embryotoxicity.
Zindikirani
Ziweto ziyenera kusamala pakadutsa masiku 45 kuchokera pamimba
Hebei Veyong pharmaceutical Co., Ltd, unakhazikitsidwa mu 2002, ili mu Shijiazhuang City, Hebei Province, China, pafupi ndi Capital Beijing.Ndi kampani yayikulu yovomerezeka ya GMP yotsimikizira za Chowona Zanyama, yokhala ndi R&D, kupanga ndi kugulitsa ma API a Chowona Zanyama, kukonzekera, zakudya zosakaniza ndi zowonjezera zowonjezera.Monga Provincial Technical Center, Veyong yakhazikitsa njira yatsopano ya R&D yamankhwala atsopano azowona zanyama, ndipo ndi kampani yodziwika bwino yaukadaulo yozikidwa pazanyama, pali akatswiri 65 aukadaulo.Veyong ili ndi zoyambira ziwiri zopangira: Shijiazhuang ndi Ordos, pomwe maziko a Shijiazhuang amatenga malo a 78,706 m2, okhala ndi zinthu 13 za API kuphatikiza Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, ndi 11, mizere yopangira jekeseni, njira yopangira jekeseni. , premix, bolus, mankhwala ndi mankhwala ophera tizilombo, ects.Veyong imapereka ma API, zokonzekera zolembera zopitilira 100, ndi ntchito za OEM & ODM.
Veyong amawona kufunikira kwakukulu ku kasamalidwe ka EHS(Environment, Health & Safety) system, ndipo adalandira ziphaso za ISO14001 ndi OHSAS18001.Veyong adalembedwa m'mabizinesi omwe akutuluka m'chigawo cha Hebei ndipo amatha kuonetsetsa kuti zinthu zikuyenda bwino.
Veyong adakhazikitsa dongosolo lathunthu la kasamalidwe kaubwino, adapeza satifiketi ya ISO9001, satifiketi ya China GMP, satifiketi ya APVMA GMP ya Australia, satifiketi ya GMP ya Ethiopia, satifiketi ya Ivermectin CEP, ndipo idapita ku US FDA.Veyong ali ndi gulu la akatswiri olembetsa, malonda ndi ntchito zaukadaulo, kampani yathu idadalitsidwa ndi chithandizo kuchokera kwamakasitomala ambiri ndi mtundu wabwino kwambiri wazinthu, zogulitsa zapamwamba kwambiri komanso ntchito zotsatsa pambuyo pa malonda, kasamalidwe kakulu ndi sayansi.Veyong wapanga mgwirizano wautali ndi mabizinesi ambiri odziwika padziko lonse lapansi ogulitsa nyama ndi zinthu zomwe zimatumizidwa ku Europe, South America, Middle East, Africa, Asia, etc. mayiko ndi zigawo zopitilira 60.
