Benzypencillin sodium ufa wa jekeseni
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Pharmacological kanthu
Pharmacological kanthu
Penicillin ndi bactericidal mankhwala ndi amphamvu antibacterial ntchito, ndi antibacterial limagwirira ndi makamaka ziletsa synthesis wa bakiteriya cell khoma mucopeptides.Mabakiteriya okhudzidwa mu gawo la kukula amagawanitsa mwamphamvu, ndipo khoma la cell liri mu gawo la biosynthesis.Pansi pa penicillin, kaphatikizidwe ka mucopeptides kumatsekedwa ndipo khoma la cell silingapangidwe, ndipo nembanemba ya cell imasweka ndikufa chifukwa cha kukakamizidwa kwa osmotic.
Penicillin ndi mankhwala ophera tizilombo toononga, makamaka motsutsana ndi mabakiteriya osiyanasiyana a gram-positive ndi ochepa a gram-negative cocci.Waukulu tcheru mabakiteriya Staphylococcus, Streptococcus, Erysipelas suis, Corynebacterium, Clostridium tetani, Actinomycetes, Bacillus anthracis, Spirochetes, etc. Osamva mycobacteria, mycoplasma, mauka, rickettsia, nocardia, bowa ndi mavairasi.
Pharmacological kanthu
Pharmacokinetics
Pambuyo mu mnofu jekeseni wa penicillin, procaine pang`onopang`ono odzipereka pambuyo kutulutsidwa kwa penicillin ndi m`deralo hydrolysis.Nthawi yayitali kwambiri ndipo kuchuluka kwa magazi kumachepa, koma zotsatira zake zimakhala zazitali kuposa penicillin.Amangokhala ndi mabakiteriya omwe amakhudzidwa kwambiri ndi penicillin, ndipo sayenera kugwiritsidwa ntchito pochiza matenda aakulu.Procaine penicillin ndi penicillin sodium (potaziyamu) atasakanizidwa ndikupangidwa kukhala jakisoni, kuchuluka kwa mankhwalawa m'magazi kumatha kuonjezedwa pakanthawi kochepa, kuti aganizire zakuchita kwanthawi yayitali komanso kuchita mwachangu.Jekeseni wamkulu wa procaine penicillin angayambitse poizoni wa procaine.
Kugwiritsa Ntchito Mankhwala
(1) Kuphatikiza kwa penicillin ndi aminoglycosides kumatha kukulitsa kuchuluka kwa mabakiteriya omwe ali ndi mabakiteriya, kotero kumapereka mphamvu yolumikizana.
(2) Mankhwala opha tizilombo toyambitsa matenda monga macrolides, tetracyclines ndi amide alcohols amasokoneza ntchito ya penicillin ndipo sayenera kugwiritsidwa ntchito limodzi.
(3) Heavy zitsulo ayoni (makamaka mkuwa, nthaka, mercury), alcohols, zidulo, ayodini, oxidizing wothandizila, kuchepetsa wothandizila, hydroxyl mankhwala, jekeseni acidic shuga kapena tetracycline hydrochloride jekeseni akhoza kuwononga ntchito penicillin ndipo n'zogwirizana Taboo.
(4) sayenera kusakanikirana ndi mankhwala ena (monga chlorpromazine hydrochloride, lincomycin hydrochloride, norepinephrine tartrate, oxytetracycline hydrochloride, tetracycline hydrochloride, mavitamini B ndi vitamini C), apo ayi turbidity, zolimba zolimba kapena mpweya.
Zizindikiro
Amagwiritsidwa ntchito makamaka pa matenda aakulu omwe amayamba chifukwa cha mabakiteriya okhudzidwa ndi penicillin, monga bovine pyometra, mastitis, fractures zovuta, etc., komanso matenda monga actinomycetes ndi leptospirosis.
Kagwiritsidwe ndi Mlingo
Onjezani madzi osabala a jakisoni kuti mupange osakaniza musanagwiritse ntchito.jakisoni mu mnofu: Mlingo umodzi, pa 1kg kulemera kwa thupi, mayunitsi 10,000 mpaka 20,000 akavalo ndi ng'ombe;20,000 mpaka 30,000 mayunitsi a nkhosa, nkhumba, ndi anyani;30,000 mpaka 40,000 mayunitsi agalu ndi amphaka.1 nthawi patsiku kwa masiku 2-3.
Zoyipa
(1) Makamaka ziwengo, zomwe zimatha kuchitika pa ziweto zambiri, koma zochitika ndizochepa.Zomwe zimachitika m'deralo zimawonetsedwa ngati madzi ndi ululu pamalo opangira jekeseni, ndipo machitidwewa ndi chikuku ndi zidzolo, zomwe zingayambitse kugwedezeka kapena imfa pazovuta kwambiri.
(2) M’zinyama zina, kuloŵerera kwa m’mimba kungathe kusonkhezeredwa.
Kusamalitsa
(1) Mankhwalawa amagwiritsidwa ntchito pochiza matenda omwe amayamba chifukwa cha mabakiteriya omwe amakhudzidwa kwambiri.
(2) Kusungunuka pang’ono m’madzi.Ngati asidi, alkali kapena oxidizing agent, idzalephera mofulumira.Choncho, jekeseni ayenera kukonzekera asanagwiritse ntchito.
(3) Samalani kuyanjana ndi kusagwirizana ndi mankhwala ena, kuti musakhudze mphamvu ya mankhwala.
Nthawi yochotsa
ng’ombe, nkhosa, ndi nkhumba masiku 28;Maola 72 kusiya mkaka
Hebei Veyong pharmaceutical Co., Ltd, unakhazikitsidwa mu 2002, ili mu Shijiazhuang City, Hebei Province, China, pafupi ndi Capital Beijing.Ndi kampani yayikulu yovomerezeka ya GMP yotsimikizira za Chowona Zanyama, yokhala ndi R&D, kupanga ndi kugulitsa ma API a Chowona Zanyama, kukonzekera, zakudya zosakaniza ndi zowonjezera zowonjezera.Monga Provincial Technical Center, Veyong yakhazikitsa njira yatsopano ya R&D yamankhwala atsopano azowona zanyama, ndipo ndi kampani yodziwika bwino yaukadaulo yozikidwa pazanyama, pali akatswiri 65 aukadaulo.Veyong ili ndi zoyambira ziwiri zopangira: Shijiazhuang ndi Ordos, pomwe maziko a Shijiazhuang amatenga malo a 78,706 m2, okhala ndi zinthu 13 za API kuphatikiza Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, ndi 11, mizere yopangira jekeseni, njira yopangira jekeseni. , premix, bolus, mankhwala ndi mankhwala ophera tizilombo, ects.Veyong imapereka ma API, zokonzekera zolembera zopitilira 100, ndi ntchito za OEM & ODM.
Veyong amawona kufunikira kwakukulu ku kasamalidwe ka EHS(Environment, Health & Safety) system, ndipo adalandira ziphaso za ISO14001 ndi OHSAS18001.Veyong adalembedwa m'mabizinesi omwe akutuluka m'chigawo cha Hebei ndipo amatha kuonetsetsa kuti zinthu zikuyenda bwino.
Veyong adakhazikitsa dongosolo lathunthu la kasamalidwe kaubwino, adapeza satifiketi ya ISO9001, satifiketi ya China GMP, satifiketi ya APVMA GMP ya Australia, satifiketi ya GMP ya Ethiopia, satifiketi ya Ivermectin CEP, ndipo idapita ku US FDA.Veyong ali ndi gulu la akatswiri olembetsa, malonda ndi ntchito zaukadaulo, kampani yathu idadalitsidwa ndi chithandizo kuchokera kwamakasitomala ambiri ndi mtundu wabwino kwambiri wazinthu, zogulitsa zapamwamba kwambiri komanso ntchito zotsatsa pambuyo pa malonda, kasamalidwe kakulu ndi sayansi.Veyong wapanga mgwirizano wautali ndi mabizinesi ambiri odziwika padziko lonse lapansi ogulitsa nyama ndi zinthu zomwe zimatumizidwa ku Europe, South America, Middle East, Africa, Asia, etc. mayiko ndi zigawo zopitilira 60.
