4% Gentamyclin sulphate jakisoni
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Chizindikiro
Maonekedwe:Izi zimakhala zopanda mtundu mpaka zachikasu kapena zobiriwira zobiriwira.
Pharmacological kanthu:PharmacodynamicGentamycinndi antibiotic ya aminoglycoside yokhala ndi antibacterial effect pa mabakiteriya osiyanasiyana a gram-negative (monga Escherichia coli, Klebsiella, Proteus, Pseudomonas aeruginosa, Pasteurella, Salmonella, etc.) ndi Staphylococcus aureus (kuphatikizapo β-lacingstrains-pro).Cocci ambiri (Streptococcus pyogenes, pneumococcus, Streptococcus faecalis, etc.), mabakiteriya anaerobic (Bacteroides kapena Clostridium), Mycobacterium tuberculosis, Rickettsia ndi bowa amalimbana ndi mankhwalawa.
Pharmacokinetics:Mayamwidwe mwachangu komanso kwathunthu pambuyo jekeseni mu mnofu.Kukhazikika kwakukulu kumafika mkati mwa ola 0,5 mpaka 1.Kupezeka kwa bioavailability kumaposa 90% kwa jakisoni wa subcutaneous kapena intramuscular.Imatulutsidwa makamaka ndi kusefera kwa glomerular ndipo imakhala 40% mpaka 80% ya mlingo womwe umaperekedwa.Theka la moyo pambuyo jekeseni mu mnofu jekeseni ndi 1.8 kwa 3.3 maola akavalo, 2.2 kwa 2.7 maola ng'ombe, 0,5 kwa 1.5 maola agalu ndi amphaka, 1 ola ng'ombe ndi nkhumba, 1 kwa 2 ora akalulu, ndi 2.3 mpaka 3.2 maola a nkhosa, njati, ng’ombe, ndi mbuzi za mkaka.
Kuyanjana ndi mankhwala:
(1) Kuphatikiza kwa Gentamycin ndi tetracycline ndi erythromycin kungakhale ndi zotsatira zotsutsana.
(2) Kuphatikiza ndi cephalosporins, dextran, diuretics wamphamvu (monga furosemide, etc.), ndi erythromycin, ototoxicity ya mankhwalawa imatha kukulitsidwa.
(3) Otsitsimula minofu yachigoba (monga succinylcholine chloride, etc.) kapena mankhwala omwe ali ndi izi angapangitse zotsatira za neuromuscular blocking za HUMIRA.
Zochita ndi kugwiritsa ntchito
Mankhwala a Aminoglycoside.Kwa matenda a gram-negative ndi mabakiteriya abwino.
Mlingo ndi makonzedwe
(1) Ototoxicity.Nthawi zambiri zimayambitsa kuwonongeka kwa vestibular mu khutu, zomwe zimatha kukulitsidwa ndi kudzikundikira kwa mankhwala omwe amaperekedwa mosalekeza motengera mlingo.
(2) Nthawi zina ziwengo.Amphaka amakhala okhudzidwa kwambiri, nthawi zonse angayambitse nseru, kusanza, salivation ndi ataxia.
(3) Mlingo waukulu ungayambitse kutsekeka kwa neuromuscular conduction.Mwangozi imfa zambiri zimachitika pambuyo mankhwala ambiri opaleshoni njira agalu ndi amphaka, pamodzi penicillin kupewa matenda.
(4) Zingayambitse nephrotoxicity yosinthika.
Kusamalitsa
(1) Gentamycin itha kugwiritsidwa ntchito limodzi ndi maantibayotiki a β-lactam pochiza matenda oopsa, koma sigwirizana akasakanizidwa mu vitro.
(2) Kuphatikiza ndi penicillin, mankhwalawa ali ndi mphamvu yolumikizana ndi streptococci.
(3) Imakhala ndi vuto la kupuma ndipo sayenera kubayidwa kudzera m'mitsempha.
(4) Mkangano ukhoza kuchitika pamodzi ndi tetracycline ndi erythromycin.
(5) Kuphatikiza ndi cephalosporins kungapangitse nephrotoxicity.
Nthawi yochotsa
Nkhumba, ng'ombe ndi nkhosa kwa masiku 40.
Kusungirako
Losindikizidwa ndi kusungidwa mu ozizira mdima.
Hebei Veyong pharmaceutical Co., Ltd, unakhazikitsidwa mu 2002, ili mu Shijiazhuang City, Hebei Province, China, pafupi ndi Capital Beijing.Ndi kampani yayikulu yovomerezeka ya GMP yotsimikizira za Chowona Zanyama, yokhala ndi R&D, kupanga ndi kugulitsa ma API a Chowona Zanyama, kukonzekera, zakudya zosakaniza ndi zowonjezera zowonjezera.Monga Provincial Technical Center, Veyong yakhazikitsa njira yatsopano ya R&D yamankhwala atsopano azowona zanyama, ndipo ndi kampani yodziwika bwino yaukadaulo yozikidwa pazanyama, pali akatswiri 65 aukadaulo.Veyong ili ndi zoyambira ziwiri zopangira: Shijiazhuang ndi Ordos, pomwe maziko a Shijiazhuang amatenga malo a 78,706 m2, okhala ndi zinthu 13 za API kuphatikiza Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, ndi 11, mizere yopangira jekeseni, njira yopangira jekeseni. , premix, bolus, mankhwala ndi mankhwala ophera tizilombo, ects.Veyong imapereka ma API, zokonzekera zolembera zopitilira 100, ndi ntchito za OEM & ODM.
Veyong amawona kufunikira kwakukulu ku kasamalidwe ka EHS(Environment, Health & Safety) system, ndipo adalandira ziphaso za ISO14001 ndi OHSAS18001.Veyong adalembedwa m'mabizinesi omwe akutuluka m'chigawo cha Hebei ndipo amatha kuonetsetsa kuti zinthu zikuyenda bwino.
Veyong adakhazikitsa dongosolo lathunthu la kasamalidwe kaubwino, adapeza satifiketi ya ISO9001, satifiketi ya China GMP, satifiketi ya APVMA GMP ya Australia, satifiketi ya GMP ya Ethiopia, satifiketi ya Ivermectin CEP, ndipo idapita ku US FDA.Veyong ali ndi gulu la akatswiri olembetsa, malonda ndi ntchito zaukadaulo, kampani yathu idadalitsidwa ndi chithandizo kuchokera kwamakasitomala ambiri ndi mtundu wabwino kwambiri wazinthu, zogulitsa zapamwamba kwambiri komanso ntchito zotsatsa pambuyo pa malonda, kasamalidwe kakulu ndi sayansi.Veyong wapanga mgwirizano wautali ndi mabizinesi ambiri odziwika padziko lonse lapansi ogulitsa nyama ndi zinthu zomwe zimatumizidwa ku Europe, South America, Middle East, Africa, Asia, etc. mayiko ndi zigawo zopitilira 60.
