250mg triclaberbanazole bolus
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Zochita zamafuta
Pharmacontus triclobendanazole ndi kalasi ya Benzimidazole, imagwiritsidwa ntchito mwapadera kukana hevication hepatication ku mibadwo yosiyanasiyana. mankhwala othandizira. Mankhwala atatha, imasokoneza kapangidwe ka microtubule ndipo ntchito ya tiziromboti, imalepheretsa kutulutsidwa kwa ma proteases a parasite. Zotsatira za triclobendazole pa nyongolotsi zimasiyana ndi chidwi, monga akuluakulu otsika kwambiri (1 ~μg / ml)
Mankhwalawa amapulumukabe kwa maola 24, ndipo ntchitoyi imafookeza kwambiri pakukula kwakukulu (10-25g / ml) kwa maola 24; Kukhazikika kwakukulu kwa 25-50μg / ml kumalepheretsa kwa maola 24. Koma kwambiri chidwi ndi mphutsi. Pofika 10 μg / ml, ntchito yonse ya maola 24 idalephereka.
Pharmacokinetics
Bioavailability wa triclobendazoazole ili pamwamba. Pambuyo m`kamwa makonzedwe 10 mg / kg thupi mu mbuzi ndi nkhosa, ma plasma mankhwala awo 15 μg / ml mu maola 24 Mtengo wa mankhwalawa wa mankhwalawa ndi 5 mpaka 20 a Annzimidazole antheminics, ndipo kuchotsa theka-moyo kuli pafupifupi maola 22. Triclobendazoni makamaka amapezeka m'matumba mu nkhosa ndi makoswe ku sulfone ndi chidebe cha chisudzo, chomwe chimamangiriza albumin ndikupitilira m'magazi oposa 7. High plasma woipa komanso kumanga kwa albumin a albumin akuwoneka kuti akuphatikizidwa ndi kutalika kwa nthawi yayitali ya antifascioli. Pambuyo pa masiku 10 a mankhwala osokoneza bongo mu Nkhosa, 95% ya mankhwalawa amachotsedwa mu ndowe, 2% imachotsedwa mkodzo, ndipo ochepera 1% amatulutsidwa mkaka.
Zochita ndi kugwiritsa ntchito
Benzimidazole anti-iscicola mankhwala. Amagwiritsidwa ntchito makamaka popewa komanso kuchiza matenda a Pisociola Hepatica matenda a ng'ombe ndi nkhosa.
Zochitika
Palibe zovuta zomwe zachitika mukamagwiritsidwa ntchito malinga ndi zomwe amafunsidwa ndi mlingo
Kusamalitsa
(1) Wolumala panthawi ya mkaka.
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(4) Sambani manja mutatha kugwiritsa ntchito
Nthawi yochotsa
Masiku 56 a ng'ombe ndi nkhosa
Kusunga
Sungani pamalopo pansipa 30 ℃.
Hebei Veyong murmaceutical Co .. Iye ndi bizinesi yayikulu ya gmp-yotsimikizika, ndi R & D, kupanga ndi kugulitsa ma vetersin apulo apis, kukonzekera, kuchuluka kwa zakudya komanso zowonjezera. Monga momwe muliri pakati, Veyong yakhazikitsa dongosolo lokhala ndi R & D kwatsopano, ndipo ndi njira zodziwika bwino zaukadaulo zowonetsera zooneratu, pali akatswiri 65. Veyong ali ndi mabasi awiri opanga: Shijazhuang ndi Dongosolo, lomwe Shijazhuang limaphimba livemotide, a acrochtoctin, pomlomo, bollos, mankhwala ophera tizilombo komanso mankhwala opha tizilombo. Veyong amapereka Apis, kukonzekera kopitilira 100 - ndi oem & odm ntchito.
Veyong amafotokoza zofunikira kwambiri pakuwongolera ma ehs (malo, azaumoyo & chitetezo), ndipo adalandira satifiketi ya iso140018008800008000080018. Veyung adalembedwa m'magulu ogulitsa mafakitale omwe ali m'chigawo cha Hebei ndipo amatha kuwonetsetsa kuti zinthu zizitha kupezeka.
Veyong adakhazikitsa dongosolo labwino kwambiri, adapeza satifiketi ya ISO90010010010010000100. Veyong ali ndi gulu la revistary la rectionation, ntchito ndi zaukadaulo, kampani yathu yayamba kuthandizidwa ndi ntchito yabwino kwambiri yogulitsa komanso yogulitsa kwambiri komanso yoyang'anira sayansi. Veyung yapanga mgwirizano wautali ndi mabizinesi ambiri ochokera ku Europe, South America, Middle East, Asia, ndi zigawo zoposa 60.
